Comprehensive directory of North Carolina chambers of commerce, connecting businesses with resources, advocacy, and networking opportunities across the state. North Carolina is home to over 200 local and regional chambers serving communities statewide.
Local Chambers
Federation Members
State Chamber Members
Counties Represented
Address: 701 Corporate Center Dr., Suite 400, Raleigh, NC 27607
Phone: (919) 836-1400
Website: ncchamber.com
Leadership: S. Lewis Ebert, President & CEO
The North Carolina Chamber is the state's largest, broad-based business advocacy organization and an affiliate of the United States Chamber of Commerce. With more than 700 member businesses from nearly every industry and county in North Carolina, the NC Chamber advocates for solutions and policies that produce a nationally competitive business climate.
Employing more than 1.7 million people statewide and comprising 99% of all businesses, North Carolina's small businesses are the lifeblood of the state's entrepreneurial spirit. The NC Chamber Small Business Council provides advocacy, affordable health care options, networking opportunities, and resources specifically designed for businesses with 1-15 full-time employees.
Website: edpnc.com
The EDPNC is a public-private organization established in 2014 by the North Carolina General Assembly to improve the economic well-being and quality of life for all North Carolinians. CNBC named North Carolina as America's Top State for Business in 2025, marking the third time the state has earned this honor in the last four years.
Address: 330 S Tryon St, Charlotte, NC 28202
Website: charlotteregion.com
The Charlotte Regional Business Alliance is a U.S. Chamber Member organization serving the Charlotte metropolitan area. The Charlotte Area Chamber of Commerce supports, serves, and strengthens members through networking, education, and resources for small businesses.
Address: 800 S Salisbury Street, Raleigh, NC 27601
Website: raleighchamber.org
The Triangle's largest business membership organization with over 1,800 member firms representing two-thirds of the private sector employment in Wake County. Monthly membership options available starting at $45/month.
Address: 111 W February One Pl, Greensboro, NC 27401
Part of the NC Chamber Federation serving the Greensboro metropolitan area and Guilford County business community.
Website: wilmingtonchamber.org
Over 1,000 businesses of all sizes representing more than 40,000 employees in southeastern North Carolina. Membership levels range from $500 to $10,000+ depending on business goals. Features a Vice President of Small Business Development and Business Retention position.
Website: ashevillechamber.org
North Carolina's 3rd largest Chamber with more than 1,500 businesses representing 80,000+ employees. Membership levels range from $450 to $8,000+ depending on business goals. Offers networking events, business education, and exclusive member savings programs.
Member organization of the NC Chamber serving Forsyth County and the Winston-Salem metropolitan area with business advocacy and networking resources.
North Carolina has over 200 local chambers of commerce serving communities across all 100 counties. Use the U.S. Chamber of Commerce Chamber Finder to locate your nearest chamber.
Website: ncsbc.net
North Carolina's largest state-supported small business assistance initiative. A Small Business Center is located at each of North Carolina's 58 community colleges to help guide entrepreneurs.
A division of the Economic Development Partnership of North Carolina providing consulting services to small businesses.
Costs vary by chamber and business size. Contact your local chamber for specific pricing and membership tiers.
Last updated on November 27, 2025