Missouri Chamber of Commerce Directory

75,000+

Member Employers

530,380

Small Businesses

1.2M

Small Business Employees

$1.1B

2025 Legislative Impact

State Chamber Leadership: The Missouri Chamber of Commerce and Industry has represented Missouri employers since 1921, providing effective advocacy before the Missouri General Assembly, government agencies, and courts to reduce taxes, limit regulation, improve education, and foster economic development opportunities.

Missouri Chamber of Commerce and Industry

State Chamber of Commerce

Organization: Missouri Chamber of Commerce and Industry

Founded: 1921

Address: 428 E. Capitol Ave., Jefferson City, MO 65101

Phone: (573) 634-3511

Website: mochamber.com

As Missouri's largest and most influential business association, the Missouri Chamber is the leading voice in the state capitol. Together with the Missouri Chamber Federation, they represent more than 75,000 employers across the state.

Key Services & Programs:

  • Legislative Advocacy: Aggressive lobbying team testifying on more issues than any other business organization in Missouri
  • Chamber Benefit Plan: Affordable health care coverage for small businesses through a self-funded MEWA model administered by Anthem Blue Cross and Blue Shield
  • Missouri 2030: Bold 15-year strategic plan to establish Missouri as an economic leader
  • Missouri Chamber Federation: Partnership with local chambers unifying advocacy efforts in Jefferson City and Washington, D.C.
  • Legal Reform: Protection against excessive litigation and workers' compensation insurance advocacy
  • Education & Workforce Development: Programs supporting skilled workforce development
  • International Trade: Export assistance and foreign market identification
  • Women's Council: Resource center supporting Missouri women in pursuing economic goals

Membership Benefits:

  • Voice representing 75,000+ Missouri employers in policy decisions
  • Access to Chamber Benefit Plan health insurance for 2-50 eligible employees
  • Discounted rates for events, seminars, and facility rentals
  • Product discounts and market analysis services
  • Assistance with regulatory issues
  • Network of industry and governmental leaders
  • Participation in Missouri 2030 strategic initiatives

Regional & Metro Chambers of Commerce

Kansas City Area

Greater Kansas City Chamber of Commerce

Address: 30 W Pershing Rd, Kansas City, MO 64108

Website: kcchamber.com

The region's largest and most influential Chamber, providing connections, advocacy, access, leadership and visibility. Member of the Missouri Major Metro Coalition providing unified business voice in Jefferson City.

Northland Regional Chamber of Commerce

Address: 4131 N Mulberry Dr, Kansas City, MO 64116

Website: northlandchamber.com

Serving the Northland region of Kansas City with business advocacy, networking, and economic development support.

Hispanic Chamber of Commerce of Greater Kansas City

Address: 107 W 10th St, Kansas City, MO 64105

Website: hispanicchamberofkc.com

Supporting Hispanic businesses and entrepreneurs in the Greater Kansas City metropolitan area.

Black Chamber of Commerce of Greater Kansas City

Address: 5737 Swope Pkwy, Kansas City, MO 64130

Website: bcckc.org

Promoting economic empowerment for Black-owned businesses in the Kansas City region.

St. Louis Area

Greater St. Louis Inc.

Address: 211 N Broadway, Saint Louis, MO 63102

Website: greaterstlinc.com

St. Louis Regional Chamber serving as business advocate and economic development leader. Member of the Missouri Major Metro Coalition.

St. Charles Regional Chamber of Commerce

Serving businesses in St. Charles County with networking, advocacy, and business development resources.

West County Chamber of Commerce

Address: 15965 Manchester Rd, Ellisville, MO 63011

Website: westcountychamber.com

Supporting businesses in West St. Louis County region.

Heartland St. Louis Black Chamber of Commerce

Promoting economic opportunities for African American businesses in the St. Louis metropolitan area.

Springfield Area

Springfield Area Chamber of Commerce

Address: 202 S John Q Hammons Pkwy, Springfield, MO

Website: springfieldchamber.com

Leading voice of business in Springfield, dedicated to fostering a thriving economic environment. Drives initiatives helping businesses of every size succeed. Member of the Missouri Major Metro Coalition and Show-Me Network partner.

Columbia Area

Columbia Chamber of Commerce

Founded: 1905

Website: comochamber.com

Voluntary, member-supported organization with 1,000+ members working together to develop, promote, and maintain a sound and healthy economic climate for Columbia.

City & Local Chambers of Commerce

Arnold Chamber of Commerce

Serving Arnold and surrounding Jefferson County communities

arnoldchamber.org

Blue Springs Chamber of Commerce

Address: 1000 W Main St, Blue Springs, MO

Supporting businesses in Blue Springs and eastern Jackson County

Branson/Lakes Area Chamber

Serving the Branson tourism and business community

Cape Girardeau Chamber

Address: 220 N Fountain St, Cape Girardeau, MO

Southeast Missouri's business leadership organization

Carthage Chamber of Commerce

Address: 402 S Garrison Ave, Carthage, MO

Serving Jasper County business community

Chesterfield Chamber

Address: 101 Chesterfield Business Pkwy, Chesterfield, MO

West St. Louis County business community

Crocker Chamber of Commerce

Rural Pulaski County business support

Cuba Chamber of Commerce

Crawford County business community

Dixon Chamber of Commerce

Serving businesses in Dixon and surrounding Pulaski County

Farmington Regional Chamber

Address: 302 N Washington St, Farmington, MO

St. Francois County business development

Grandview Chamber

Southern Jackson County business community

Hermann Area Chamber

Address: 150 Market St, Hermann, MO

Gasconade County tourism and business support

Jefferson City Area Chamber

Address: 213 Adams St, Jefferson City, MO

State capital business community

Joplin Area Chamber

Southwest Missouri business leadership, Show-Me Network partner

Lake West Chamber

Sunrise Beach area business community at Lake of the Ozarks

O'Fallon Chamber

Eastern Missouri business development

Perryville Chamber

Perry County business community

Rolla Area Chamber

Address: 1311 Kingshighway, Rolla, MO 65401

Phelps County business and education community

Salem Area Chamber & Visitors Center

Address: 1136 S Main, Salem, MO

Dent County business and tourism

Sikeston Chamber

Southeast Missouri business development

St. James Chamber of Commerce

Phelps County business community

St. Joseph Chamber

Northwest Missouri business leadership, Show-Me Network partner

Steelville Chamber of Commerce

Crawford County business support

Table Rock Lake Chamber

Branson West area tourism and business

Warrensburg Chamber

Address: 100 S Holden St, Warrensburg, MO

Johnson County business community

Waynesville-St. Robert Chamber

Pulaski County business and military community support

West Plains Chamber

South-central Missouri business community

Economic Development & Business Support Organizations

Missouri Partnership

Website: missouripartnership.com

Public-private economic development organization dedicated to making business expansion into Missouri smooth and seamless. Provides complimentary support with site selection, incentive programs, and workforce assistance.

Missouri Department of Economic Development

Website: ded.mo.gov

State agency creating an environment encouraging economic growth by supporting Missouri's businesses, strengthening communities, developing workforce, and maintaining quality of life.

Missouri Small Business Development Centers

Website: sbdc.missouri.edu

Delivers up-to-date counseling, training, and technical assistance in all aspects of small business management across Missouri.

Economic Development Corporation of Kansas City

Website: edckc.com

Administers Kansas City's economic development strategy creating quality jobs, revitalizing neighborhoods, and empowering small businesses.

Missouri Technology Corporation

Public-private partnership fostering innovation and entrepreneurship within Missouri, providing strategic investments to high-tech companies.

Missouri Enterprise

Offers assistance to manufacturers to improve technology and processes, supporting manufacturing competitiveness.

Missouri One Start

Supports eligible businesses by customizing recruitment strategies and providing resources for tailored training at no cost to qualifying companies.

Chamber of Commerce Executives of Missouri

Website: ccemo.org

Provides training, education, and networking for chamber executives across Missouri.

Special Initiatives & Programs

Missouri Major Metro Coalition

Partnership between Missouri's four largest chambers (St. Louis Regional Chamber, Greater Kansas City Chamber, Springfield Area Chamber, and Missouri Chamber) providing unified business voice in Jefferson City.

Show-Me Network

Initiative bringing together entrepreneurs and community leaders from small and rural communities across Missouri. Partners include Joplin, Springfield, St. Joseph chambers, plus at least 18 economic development groups.

Goldman Sachs 10,000 Small Businesses

$100 million investment in rural Missouri communities providing business education through State Fair Community College, $75 million in loans via CDFIs, and capacity-building grants.

Missouri Works Program

State incentive program supporting job creation and capital investment for businesses expanding or relocating to Missouri.

Rural & Small Community Support

Rural Business Support Resources

  • Missouri Rural Enterprise & Innovation Center: Show-Me Network partner supporting rural entrepreneurship
  • Ozarks Small Business Incubator: Network partner providing startup support in southwest Missouri
  • MU Extension - Connecting Entrepreneurial Communities: Helps rural communities build resources supporting innovation and entrepreneurship through twice-monthly webinars
  • USDA Rural Development: Offers loans, loan guarantees, and grants for housing, community, business, utility, and cooperative programs
  • Missouri Rural Resource Locator: Directory connecting rural businesses to development resources
  • Innovate SOMO: Technology-based development organization in Cape Girardeau creating Show-Me Network
  • Codefi: Tech-based development nonprofit deploying innovation ecosystems in rural regions, producing software-focused jobs and providing pre-seed capital access

Frequently Asked Questions

The Missouri Chamber of Commerce and Industry is the state's largest and most influential business association, founded in 1921. It represents more than 75,000 employers across Missouri through its membership and Missouri Chamber Federation partnership. The Chamber provides aggressive legislative advocacy in Jefferson City, lobbies on more issues than any other business organization in the state, and offers valuable member benefits including the Chamber Benefit Plan for health insurance. Their mission is to protect and advance Missouri employers through effective representation before the Missouri General Assembly, government agencies, and courts to reduce taxes, limit regulation, improve education, and foster economic development opportunities.

According to the U.S. Small Business Administration, Missouri has 530,380 small businesses, which represent 99.4% of all businesses in the state. These small businesses employ approximately 1.2 million Missourians, making up 46.2% of the state's workforce. Small businesses are the backbone of Missouri's economy, spanning diverse industries from agriculture and manufacturing to technology and professional services. The Missouri Chamber and local chambers across the state provide essential support services, advocacy, and networking opportunities to help these businesses succeed and grow.

The Missouri Chamber Benefit Plan is a health care coverage program designed specifically for small businesses with 2 to 50 eligible employees. It uses a MEWA (Multiple Employer Welfare Arrangement) model allowing small business employers to join together in a self-funded pool to share overall claims risk, making health insurance more affordable. The plan is administered by Anthem Blue Cross and Blue Shield and powered by the Missouri Chamber Federation. Members can access medical, dental, and vision benefits, with potential discounts for bundling coverage. The Eastern Region offers fully integrated Health Savings Accounts through Central Bank. A network of certified insurance brokers trained by the Chamber provides detailed quotes and helps businesses save money while giving employees access to quality health care.

The Missouri Chamber Federation is a partnership between the Missouri Chamber of Commerce and Industry and local chambers across the state designed to unite advocacy efforts in Jefferson City and Washington, D.C. The Federation creates a network of Missouri's strongest chambers of commerce, providing grassroots support and unified voice for business interests. Together with the state Chamber, the Federation represents more than 75,000 employers statewide. Federation members benefit from coordinated advocacy initiatives, shared resources, professional development opportunities through the Chamber of Commerce Executives of Missouri (CCEM), and collective bargaining power for programs like the Chamber Benefit Plan. The Federation strengthens the connection between local business needs and state-level policy decisions.

Missouri 2030 is a bold, comprehensive 15-year strategic plan developed by the Missouri Chamber of Commerce and Industry to help establish Missouri as a leader in several key economic measurements. The initiative brings together business leaders, government officials, and community stakeholders to set long-term economic vision and goals for the state. Missouri 2030 focuses on critical areas including workforce development, infrastructure improvement, education quality, tax competitiveness, regulatory environment, and innovation capacity. Chamber members can actively participate in shaping Missouri's economic future by getting involved in Missouri 2030 working groups and initiatives. The plan emphasizes measurable outcomes and accountability to ensure Missouri remains competitive in attracting and retaining businesses while improving quality of life for residents.

The Missouri Major Metro Coalition is a partnership between the four largest chambers in Missouri: the St. Louis Regional Chamber of Commerce, the Greater Kansas City Chamber of Commerce, the Springfield Area Chamber of Commerce, and the Missouri Chamber of Commerce and Industry. This coalition provides the business community a more powerful and unified voice in Jefferson City on state legislative and regulatory matters. By combining the resources and influence of Missouri's major metropolitan business organizations, the Coalition ensures that business priorities from across the state receive strong representation in policy decisions. The Coalition focuses on issues affecting large-scale economic development, workforce policies, infrastructure investment, and business climate improvements that benefit all regions of Missouri.

Rural Missouri businesses have access to extensive support through multiple programs and organizations. The Show-Me Network brings together entrepreneurs and community leaders from small and rural communities across Missouri, with at least 18 chambers of commerce and economic development groups serving as community partners. Goldman Sachs' $100 million Investment in Rural Communities provides $75 million to community development financial institutions (CDFIs) for small business loans, $15 million for business education programs through State Fair Community College, and $10 million in capacity-building grants. The Missouri Rural Enterprise & Innovation Center, Ozarks Small Business Incubator, and Codefi provide startup support and innovation ecosystem development. MU Extension's Connecting Entrepreneurial Communities program offers twice-monthly webinars on rural economic development topics. USDA Rural Development provides loans and grants for business, housing, and community programs. Local chambers throughout rural Missouri offer networking, advocacy, and business development resources tailored to small-town needs.

You can find your local Missouri chamber of commerce through several resources. The U.S. Chamber of Commerce offers an interactive Chamber Finder tool at uschamber.com/co/chambers/missouri where you can search by city or region. The Missouri Chamber of Commerce website (mochamber.com) provides links to Federation member chambers across the state. County government websites often list local chambers serving their communities - for example, Jackson County and Jefferson County maintain chamber directories on their official sites. Regional planning commissions like the Meramec Regional Planning Commission list chambers in their service areas. You can also search online for "[Your City] Missouri Chamber of Commerce" to find contact information. Most chambers maintain websites with membership information, event calendars, and business directories. If you're unsure which chamber serves your area, contact the Missouri Chamber of Commerce at (573) 634-3511 for referral assistance.

Missouri offers comprehensive economic development resources through multiple state and regional organizations. The Missouri Department of Economic Development (ded.mo.gov) provides programs supporting business growth, workforce development, and community development. Missouri Partnership (missouripartnership.com) offers complimentary support for businesses expanding into Missouri, including site selection assistance, incentive program navigation, and workforce solutions. The Missouri Works Program provides financial incentives for job creation and capital investment. Missouri One Start offers customized recruitment strategies and no-cost training for eligible businesses. Missouri Small Business Development Centers (sbdc.missouri.edu) deliver free counseling and technical assistance across the state. Missouri Enterprise assists manufacturers with technology and process improvements. The Missouri Technology Corporation provides strategic investments to high-tech companies. Regional organizations like the Economic Development Corporation of Kansas City and local chambers offer targeted support for businesses in their areas. Export assistance is available through DED's international trade programs. The Women's Council connects women entrepreneurs to advisory services and resources.

The Missouri Chamber of Commerce and Industry provides the most aggressive and professional lobbying team among Missouri business organizations, testifying on more issues more often than any other group in the state capitol. During the 2025 legislative session alone, the Chamber's advocacy work resulted in an estimated $1.1 billion impact for Missouri businesses. The Chamber represents employers before the Missouri General Assembly, government agencies, and courts on critical issues including tax reduction, regulatory limitation, education improvement, legal reform, workers' compensation insurance, health care policy, workforce development, international trade, state transportation funding, and employment law. No other pro-business organization matches the Chamber's reach and influence in Jefferson City. Through the Missouri Chamber Federation, local chambers across the state unite their grassroots advocacy efforts with state-level lobbying. The Missouri Major Metro Coalition amplifies the voice of business interests in policy decisions. The Chamber also maintains a Political Action Committee (PAC) supporting pro-business candidates. Members gain direct access to this powerful advocacy network representing 75,000+ employers.

Related Resources

Last updated on November 27, 2025